The plant LINC complex at the nuclear envelope.

Abstract : Significant advances in understanding the plant nuclear envelope have been made over the past few years; indeed, knowledge of the protein network at the nuclear envelope is rapidly growing. One such network, the linker of nucleoskeleton and cytoskeleton (LINC) complex, is known in animals to connect chromatin to the cytoskeleton through the nuclear envelope. The LINC complex is made of Sad1/Unc84 (SUN) and Klarsicht/Anc1/Syne1 homology (KASH) proteins which have been recently characterized in plants. SUN proteins are located within the inner nuclear membrane, while the KASH proteins are included into the outer nuclear membrane. SUN and KASH domains interact and bridge the two nuclear membranes. In Arabidopsis, KASH proteins also interact with the tryptophan-proline-proline (WPP) domain-interacting tail-anchored protein 1 (WIT1), associated with the nuclear pore complex and with myosin XI-i which directly interacts with the actin cytoskeleton. Although evidence for a plant LINC complex connecting the nucleus to the cytoskeleton is growing, its interaction with chromatin is still unknown, but knowledge gained from animal models strongly suggests its existence in plants. Possible functions of the plant LINC complex in cell division, nuclear shape, and chromatin organization are discussed.
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Article dans une revue
Chromosome Research, Springer Verlag, 2014, 22 (2), pp.241-52. 〈10.1007/s10577-014-9419-7〉
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https://hal-clermont-univ.archives-ouvertes.fr/hal-01051307
Contributeur : Camille Meyer <>
Soumis le : vendredi 25 juillet 2014 - 16:58:39
Dernière modification le : jeudi 11 janvier 2018 - 06:23:14

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Christophe Tatout, David E Evans, Emmanuel Vanrobays, Aline V Probst, Katja Graumann. The plant LINC complex at the nuclear envelope.. Chromosome Research, Springer Verlag, 2014, 22 (2), pp.241-52. 〈10.1007/s10577-014-9419-7〉. 〈hal-01051307〉

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