Mediterranean semi-arid plant Astragalus armatus as a source of bioactive galactomannan

Abstract : A water-soluble polysaccharide fraction (WSPF) was extracted and purified from Astragalus armatus Lam. (Fabaceae), a spontaneous plant found in North Algerian Sahara. The structural features of WSPF were evaluated by colorimetric assays, Fourier transform infrared (FTIR) spectroscopy, high performance anion exchange chromatography with pulsed amperometric detection (HPAEC-PAD) and gas chromatography coupled to mass spectrometry (GC/MS). WSPF was a galactomannan-rich fraction, with a β-(1,4)-d-manp backbone with α-(1,6)-d-galp branches, and a Man:Gal ratio of 1.13. Besides, the anti-complement activity and the antioxidant potential (DPPH and hydroxyl radicals) of WSPF were evaluated. The results exhibited an anti-complementary activity, with an IC50 value of 0.39 mg/mL of the fraction, better than for heparin (0.58 mg/mL). Moreover, WSPF possessed a notable antioxidant activity on DPPH radical with an IC50 of 330 µg/mL.
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Bioactive Carbohydrates and Dietary Fibre, Elsevier, 2015, 5 (1), pp.10 - 18. 〈10.1016/j.bcdf.2014.11.002〉
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https://hal-clermont-univ.archives-ouvertes.fr/hal-01660708
Contributeur : Guillaume Pierre <>
Soumis le : lundi 11 décembre 2017 - 11:58:17
Dernière modification le : mardi 16 octobre 2018 - 10:48:01

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Zakaria Boual, Guillaume Pierre, Cédric Delattre, Fatima Benaoun, Emmanuel Petit, et al.. Mediterranean semi-arid plant Astragalus armatus as a source of bioactive galactomannan. Bioactive Carbohydrates and Dietary Fibre, Elsevier, 2015, 5 (1), pp.10 - 18. 〈10.1016/j.bcdf.2014.11.002〉. 〈hal-01660708〉

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